If you expect the best of the best, enjoy outstanding service and experience luxury like no other in Lake Nona 5-star properties. Find the best deals and unwind in style at iconic five star hotels in Lake Nona. These world class Lake Nona hotels offer luxurious accommodations with premium locations. Check out this list of Lake Nona ultra-opulent hotels to pamper yourself. From modern to classic the Lake Nona area hotels offer something for your specific liking.